Researchers associate certain gut bacteria with irritable bowel syndrome

November 25th – Researchers have found a link between a particular gut flora, Brachyspira, and the incidence of irritable bowel syndrome, according to a study published Wednesday in the journal Gut.

According to researchers at Gothenburg University in Sweden, this finding could lead to new drugs and treatments for diseases that affect the large intestine with cramps, abdominal pain, bloating, gas, diarrhea, or constipation.

According to the International Foundation for Gastrointestinal Disorders, the syndrome affects 25 to 45 million people in the United States, most of whom are women, affecting 5% to 10% of the world’s population.

Researchers used intestinal biopsy to determine a link between Brachyspyra bacteria, which are usually hidden in the mucous layer and are generally unnoticed by sampling, a Wednesday press release said.

“Unlike most other gut flora, Brachyspira is in direct contact with cells. [of the intestines] And cover those surfaces. I continued to discover Brachyspyra in more and more IBS patients, but I was very surprised when it was not discovered in healthy individuals. “

“We need to answer a lot of questions, but we hope to find a treatable cause of IBS in at least some patients,” said Gothenburg researcher Jabber.

Bacterial presence was significantly more common in IBS cases than in the general population investigated.

Bacteria were found in 19 of 62 patients with IBS, compared with 0 of the 31 volunteers who were not affected by the disease and were used as controls.

Bacteria were common in patients with diarrhea, the researchers said.

“This study suggests that this bacterium can be found in about one-third of IBS patients,” said study co-author Magnus Simren.

“We would like to see if this can be confirmed in a larger study, and we will also investigate whether Brachyspira causes symptoms in IBS and how it does. Our findings show that It may open up entirely new opportunities to treat and in some cases cure some IBS. Patients. ” Simren, a professor of gastroenterology at the Saar Glenska Academy in Gothenburg and a senior consultant at the Saar Glenska University Hospital, said.

Researchers associate certain gut bacteria with irritable bowel syndrome

Source link Researchers associate certain gut bacteria with irritable bowel syndrome

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